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A small-molecule inhibitor of the ribonucleolytic activity of human angiogenin that possesses antitumor activity
The results of previous preclinical and clinical studies have identified angiogenin (ANG) as a potentially important target for anticancer therapy. Here we report the design and implementation of a high-throughput screening assay to identify small molecules that bind to the ribonucleolytic active si...
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| Huvudupphovsmän: | , , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
National Academy of Sciences
2002
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC126625/ https://ncbi.nlm.nih.gov/pubmed/12118120 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152342999 |
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