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A small-molecule inhibitor of the ribonucleolytic activity of human angiogenin that possesses antitumor activity

The results of previous preclinical and clinical studies have identified angiogenin (ANG) as a potentially important target for anticancer therapy. Here we report the design and implementation of a high-throughput screening assay to identify small molecules that bind to the ribonucleolytic active si...

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Bibliografiska uppgifter
Huvudupphovsmän: Kao, Richard Y. T., Jenkins, Jeremy L., Olson, Karen A., Key, Marc E., Fett, James W., Shapiro, Robert
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2002
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC126625/
https://ncbi.nlm.nih.gov/pubmed/12118120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.152342999
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