A small-molecule inhibitor of the ribonucleolytic activity of human angiogenin that possesses antitumor activity

The results of previous preclinical and clinical studies have identified angiogenin (ANG) as a potentially important target for anticancer therapy. Here we report the design and implementation of a high-throughput screening assay to identify small molecules that bind to the ribonucleolytic active si...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Kao, Richard Y. T., Jenkins, Jeremy L., Olson, Karen A., Key, Marc E., Fett, James W., Shapiro, Robert
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 2002
Témata:	Biological Sciences
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126625/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12118120/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.152342999
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