A small-molecule inhibitor of the ribonucleolytic activity of human angiogenin that possesses antitumor activity
The results of previous preclinical and clinical studies have identified angiogenin (ANG) as a potentially important target for anticancer therapy. Here we report the design and implementation of a high-throughput screening assay to identify small molecules that bind to the ribonucleolytic active si...
Αποθηκεύτηκε σε:
| Εκδόθηκε σε: | Proc Natl Acad Sci U S A |
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| Κύριοι συγγραφείς: | , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
National Academy of Sciences
2002
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126625/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12118120/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.152342999 |
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