Angiogenin abolishes cell-free protein synthesis by specific ribonucleolytic inactivation of ribosomes.

Angiogenin is a potent inhibitor of cell-free protein synthesis. When incubated with rabbit reticulocyte lysate at a concentration of 40-60 nM, it completely abolishes the capacity of the lysate to support protein synthesis. The inhibition appears to be due to its ribonucleolytic activity since it (...

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Detaylı Bibliyografya
Asıl Yazarlar: St Clair, D K, Rybak, S M, Riordan, J F, Vallee, B L
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 1987
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC299536/
https://ncbi.nlm.nih.gov/pubmed/3479795
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