Llwytho...

Role of glutamine-117 in the ribonucleolytic activity of human angiogenin.

The crystal structure of human angiogenin (reported in the preceding paper in this issue) reveals that the site that corresponds to the pyrimidine binding site of RNase A is obstructed by Gln-117. Mutation of this residue to Ala and Gly is here found to increase activity 11- to 18-fold and 21- to 30...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Russo, N, Shapiro, R, Acharya, K R, Riordan, J F, Vallee, B L
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1994
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC43486/
https://ncbi.nlm.nih.gov/pubmed/8159680
Tagiau: Ychwanegu Tag
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