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The Coagulation System Contributes to αVβ6 Integrin Expression and Liver Fibrosis Induced by Cholestasis

Chronic injury to intrahepatic bile duct epithelial cells (BDECs) elicits expression of various mediators, including the αVβ6 integrin, promoting liver fibrosis. We tested the hypothesis that tissue factor (TF)-dependent thrombin generation and protease activated receptor-1 (PAR-1) activation contri...

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Bibliografische gegevens
Hoofdauteurs: Sullivan, Bradley P., Weinreb, Paul H., Violette, Shelia M., Luyendyk, James P.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Investigative Pathology 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993265/
https://ncbi.nlm.nih.gov/pubmed/21037076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100425
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