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The Coagulation System Contributes to αVβ6 Integrin Expression and Liver Fibrosis Induced by Cholestasis

Chronic injury to intrahepatic bile duct epithelial cells (BDECs) elicits expression of various mediators, including the αVβ6 integrin, promoting liver fibrosis. We tested the hypothesis that tissue factor (TF)-dependent thrombin generation and protease activated receptor-1 (PAR-1) activation contri...

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書誌詳細
主要な著者: Sullivan, Bradley P., Weinreb, Paul H., Violette, Shelia M., Luyendyk, James P.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Investigative Pathology 2010
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993265/
https://ncbi.nlm.nih.gov/pubmed/21037076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100425
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