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Inhibition of the α(v)β(6) integrin leads to limited alteration of TGF-α-induced pulmonary fibrosis

A number of growth factors and signaling pathways regulate matrix deposition and fibroblast proliferation in the lung. The epidermal growth factor receptor (EGFR) family of receptors and the transforming growth factor-β (TGF-β) family are active in diverse biological processes and are central mediat...

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Bibliografske podrobnosti
Main Authors: Madala, Satish K., Korfhagen, Thomas R., Schmidt, Stephanie, Davidson, Cynthia, Edukulla, Ramakrishna, Ikegami, Machiko, Violette, Shelia M., Weinreb, Paul H., Sheppard, Dean, Hardie, William D.
Format: Artigo
Jezik:Inglês
Izdano: American Physiological Society 2014
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Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3989722/
https://ncbi.nlm.nih.gov/pubmed/24508732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00357.2013
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