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αvβ6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse

The transforming growth factor (TGF)-β-inducible integrin αvβ6 is preferentially expressed at sites of epithelial remodeling and has been shown to bind and activate latent precursor TGF-β. Herein, we show that αvβ6 is overexpressed in human kidney epithelium in membranous glomerulonephritis, diabete...

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Библиографические подробности
Главные авторы: Hahm, Kyungmin, Lukashev, Matvey E., Luo, Yi, Yang, William J., Dolinski, Brian M., Weinreb, Paul H., Simon, Kenneth J., Chun Wang, Li, Leone, Diane R., Lobb, Roy R., McCrann, Donald J., Allaire, Normand E., Horan, Gerald S., Fogo, Agnes, Kalluri, Raghu, Shield, Charles F., Sheppard, Dean, Gardner, Humphrey A., Violette, Shelia M.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Investigative Pathology 2007
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762706/
https://ncbi.nlm.nih.gov/pubmed/17200187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060158
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