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αvβ6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse
The transforming growth factor (TGF)-β-inducible integrin αvβ6 is preferentially expressed at sites of epithelial remodeling and has been shown to bind and activate latent precursor TGF-β. Herein, we show that αvβ6 is overexpressed in human kidney epithelium in membranous glomerulonephritis, diabete...
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| Hoofdauteurs: | , , , , , , , , , , , , , , , , , , |
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| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
American Society for Investigative Pathology
2007
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1762706/ https://ncbi.nlm.nih.gov/pubmed/17200187 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060158 |
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