αvβ6 Integrin Regulates Renal Fibrosis and Inflammation in Alport Mouse

The transforming growth factor (TGF)-β-inducible integrin αvβ6 is preferentially expressed at sites of epithelial remodeling and has been shown to bind and activate latent precursor TGF-β. Herein, we show that αvβ6 is overexpressed in human kidney epithelium in membranous glomerulonephritis, diabete...

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Autores principales: Hahm, Kyungmin, Lukashev, Matvey E., Luo, Yi, Yang, William J., Dolinski, Brian M., Weinreb, Paul H., Simon, Kenneth J., Chun Wang, Li, Leone, Diane R., Lobb, Roy R., McCrann, Donald J., Allaire, Normand E., Horan, Gerald S., Fogo, Agnes, Kalluri, Raghu, Shield, Charles F., Sheppard, Dean, Gardner, Humphrey A., Violette, Shelia M.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Investigative Pathology 2007
Materias:
Regular Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1762706/
https://ncbi.nlm.nih.gov/pubmed/17200187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2007.060158
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