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Plasticity of Cytochrome P450 2B4 as Investigated by Hydrogen-Deuterium Exchange Mass Spectrometry and X-ray Crystallography

Crystal structures of the xenobiotic metabolizing cytochrome P450 2B4 have demonstrated markedly different conformations in the presence of imidazole inhibitors or in the absence of ligand. However, knowledge of the plasticity of the enzyme in solution has remained scant. Thus, hydrogen-deuterium ex...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Wilderman, P. Ross, Shah, Manish B., Liu, Tong, Li, Sheng, Hsu, Simon, Roberts, Arthur G., Goodlett, David R., Zhang, Qinghai, Woods, Virgil L., Stout, C. David, Halpert, James R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Biochemistry and Molecular Biology 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992292/
https://ncbi.nlm.nih.gov/pubmed/20880847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.180646
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