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Daxx, a Novel Fas-Binding Protein That Activates JNK and Apoptosis

The Fas cell surface receptor induces apoptosis upon receptor oligomerization. We have identified a novel signaling protein, termed Daxx, that binds specifically to the Fas death domain. Overexpression of Daxx enhances Fas-mediated apoptosis and activates the Jun N-terminal kinase (JNK) pathway. A C...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Yang, Xiaolu, Khosravi-Far, Roya, Chang, Howard Y., Baltimore, David
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 1997
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2989411/
https://ncbi.nlm.nih.gov/pubmed/9215629
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!