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Daxx plays a novel role in T cell survival but is dispensable in Fas-induced apoptosis
Daxx was originally isolated as a Fas-binding protein. However, the in vivo function of Daxx in Fas-induced apoptosis has remained enigmatic. Fas plays an important role in homeostasis in the immune system. Fas gene mutations lead to autoimmune-lymphoproliferation (lpr) diseases characterized by hyp...
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| Gepubliceerd in: | PLoS One |
|---|---|
| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Public Library of Science
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5354431/ https://ncbi.nlm.nih.gov/pubmed/28301594 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174011 |
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