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Daxx plays a novel role in T cell survival but is dispensable in Fas-induced apoptosis

Daxx was originally isolated as a Fas-binding protein. However, the in vivo function of Daxx in Fas-induced apoptosis has remained enigmatic. Fas plays an important role in homeostasis in the immune system. Fas gene mutations lead to autoimmune-lymphoproliferation (lpr) diseases characterized by hyp...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Li, Jinghe, Qian, Liangyue, Dowling, John P., Curcione, Christine, Kurup, Drishya, Zhang, Jianke
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5354431/
https://ncbi.nlm.nih.gov/pubmed/28301594
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174011
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