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Human Daxx regulates Fas-induced apoptosis from nuclear PML oncogenic domains (PODs).
Daxx was first identified as a protein that binds the cytosolic domain of Fas and links this receptor to an apoptosis pathway involving activation of Jun N-terminal kinase (JNK). We show here that cells overexpressing the human homolog of Daxx (hDaxx) display enhanced sensitivity to apoptosis induce...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171669/ https://ncbi.nlm.nih.gov/pubmed/10545115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.21.6037 |
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