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4-Hydroxynonenal self-limits Fas-mediated DISC independent apoptosis by promoting export of Daxx from nucleus to cytosol and its binding to Fas
Previously, we have shown that 4-hydroxynonenal (4-HNE) induces Fas-mediated apoptosis in HLE B-3 cells through a pathway which is independent of FasL, FADD, procaspase8-and DISC (Li, J. et al. Biochemistry, 45, 12253-12264). The involvement of Daxx has also been suggested in this pathway but its ro...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2564820/ https://ncbi.nlm.nih.gov/pubmed/18069800 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi701559f |
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