4-Hydroxynonenal induces p53-mediated apoptosis in retinal pigment epithelial cells

4-Hydroxynonenal (4-HNE) has been suggested to be involved in stress-induced signaling for apoptosis. In present studies, we have examined the effects of 4-HNE on the intrinsic apoptotic pathway associated with p53 in human retinal pigment epithelial (RPE and ARPE-19) cells. Our results show that 4-...

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Bibliographische Detailangaben
Hauptverfasser: Sharma, Abha, Sharma, Rajendra, Chaudhary, Pankaj, Vatsyayan, Rit, Pearce, Virginia, Jeyabal, Prince V.S., Zimniak, Piotr, Awasthi, Sanjay, Awasthi, Yogesh C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664083/
https://ncbi.nlm.nih.gov/pubmed/18930016
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2008.09.016
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