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Components of the Rb pathway are critical targets of UV mutagenesis in a murine melanoma model
Epidemiological studies support a link between melanoma risk and UV exposure early in life, yet the molecular targets of UV's mutagenic actions are not known. By using well characterized murine models of melanoma, we provide genetic and molecular evidence that identifies components of the Rb pa...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
The National Academy of Sciences
2003
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC298754/ https://ncbi.nlm.nih.gov/pubmed/12538879 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0336397100 |
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