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Dual Inactivation of RB and p53 Pathways in RAS-Induced Melanomas
The frequent loss of both INK4a and ARF in melanoma raises the question of which INK4a-ARF gene product functions to suppress melanoma genesis in vivo. Moreover, the high incidence of INK4a-ARF inactivation in transformed melanocytes, along with the lack of p53 mutation, implies a cell type-specific...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86838/ https://ncbi.nlm.nih.gov/pubmed/11238948 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.6.2144-2153.2001 |
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