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Metastasis in an Orthotopic Murine Model of Melanoma is Independent of RAS/RAF Mutation

Melanoma is the most lethal skin tumor, in large part because of a propensity for early metastasis. Good models of this most clinically relevant feature of melanoma are lacking. Here we report the development of an in vivo model of metastasis that relies on orthotopic injection of GFP-tagged lines i...

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Auteurs principaux: Rozenberg, Gabriela I., Monahan, Kimberly B., Torrice, Chad, Bear, James E., Sharpless, Norman E.
Format: Artigo
Langue:Inglês
Publié: 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2972650/
https://ncbi.nlm.nih.gov/pubmed/20679910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CMR.0b013e328336ee17
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