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What’s So Special about RB?

RB, p107, and p130 are highly related proteins, each capable of regulating cellular proliferation. However, only RB is frequently mutated in cancer. In this issue of Cancer Cell, Chicas et al. shed new light on this conundrum, defining a “special,” nonredundant role for RB in promoting cellular sene...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Burd, Christin E., Sharpless, Norman E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725986/
https://ncbi.nlm.nih.gov/pubmed/20385355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.03.010
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