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What’s So Special about RB?

RB, p107, and p130 are highly related proteins, each capable of regulating cellular proliferation. However, only RB is frequently mutated in cancer. In this issue of Cancer Cell, Chicas et al. shed new light on this conundrum, defining a “special,” nonredundant role for RB in promoting cellular sene...

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Bibliographic Details
Main Authors: Burd, Christin E., Sharpless, Norman E.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3725986/
https://ncbi.nlm.nih.gov/pubmed/20385355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2010.03.010
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