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Low-copy piggyBac transposon mutagenesis in mice identifies genes driving melanoma
Despite considerable efforts to sequence hypermutated cancers such as melanoma, distinguishing cancer-driving genes from thousands of recurrently mutated genes remains a significant challenge. To circumvent the problematic background mutation rates and identify new melanoma driver genes, we carried...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3780872/ https://ncbi.nlm.nih.gov/pubmed/24003131 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1314435110 |
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