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PiggyBac Transposon Mutagenesis: A Tool for Cancer Gene Discovery in Mice
Transposons are mobile DNA segments that can disrupt gene function by inserting in or near genes. Here we show that insertional mutagenesis by the PiggyBac transposon can be used for cancer gene discovery in mice. PiggyBac transposition in genetically engineered transposon/transposase mice induced c...
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| 主要な著者: | , , , , , , , , , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2010
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3719098/ https://ncbi.nlm.nih.gov/pubmed/20947725 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1193004 |
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