Sequence-specific intercalating agents: intercalation at specific sequences on duplex DNA via major groove recognition by oligonucleotide-intercalator conjugates.

An acridine derivative was covalently linked to the 5' end of a homopyrimidine oligonucleotide. Specific binding to a homopurine-homopyrimidine sequence of duplex DNA was demonstrated by spectroscopic studies (absorption and fluorescence) and by "footprinting" experiments with a coppe...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Sun, J S, François, J C, Montenay-Garestier, T, Saison-Behmoaras, T, Roig, V, Thuong, N T, Hélène, C
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1989
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC298461/
https://ncbi.nlm.nih.gov/pubmed/2594761
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