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Graded enhancement of p53 binding to CREB-binding protein (CBP) by multisite phosphorylation
The transcriptional activity of p53 is regulated by a cascade of posttranslational modifications. Although acetylation of p53 by CREB-binding protein (CBP)/p300 is known to be indispensable for p53 activation, the role of phosphorylation, and in particular multisite phosphorylation, in activation of...
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| Główni autorzy: | , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
National Academy of Sciences
2010
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2984141/ https://ncbi.nlm.nih.gov/pubmed/20962272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1013078107 |
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