Isolation of cDNAs encoding a human protein that binds selectively to DNA modified by the anticancer drug cis-diamminedichloroplatinum(II)

DNA modified by the antitumor drug cis-diamminedichloroplatinum(II) (cis-DDP or cisplatin) was used to identify a factor in mammalian cells that binds to cis-DDP-damaged DNA and hence may play a role in repair. This factor selectively recognizes double-stranded DNA fragments modified by cis-DDP or [...

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Bibliografische gegevens
Hoofdauteurs: Toney, J H, Donahue, B A, Kellett, P J, Bruhn, S L, Essigmann, J M, Lippard, S J
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1989
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC298274/
https://ncbi.nlm.nih.gov/pubmed/2530581
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