Antibodies elicited against cis-diamminedichloroplatinum(II)-modified DNA are specific for cis-diamminedichloroplatinum(II)-DNA adducts formed in vivo and in vitro.

Ítems similars

• Polyclonal antibodies to quantitate cis-diamminedichloroplatinum(II)--DNA adducts in cancer patients and animal models.
  per: Poirier, M C, et al.
  Publicat: (1985)
• Quantitation of cis-diamminedichloroplatinum II (cisplatin)-DNA-intrastrand adducts in testicular and ovarian cancer patients receiving cisplatin chemotherapy.
  per: Reed, E, et al.
  Publicat: (1986)
• Mutagenic and genotoxic effects of DNA adducts formed by the anticancer drug cis-diamminedichloroplatinum(II).
  per: Yarema, K J, et al.
  Publicat: (1995)
• Monoclonal antibodies to DNA modified with cis- or trans-diamminedichloroplatinum(II).
  per: Sundquist, W I, et al.
  Publicat: (1987)
• The major adduct of the antitumor drug cis-diamminedichloroplatinum(II) with DNA bends the duplex by approximately equal to 40 degrees toward the major groove.
  per: Rice, J A, et al.
  Publicat: (1988)