Ethidium bromide changes the nuclease-sensitive DNA binding sites of the antitumor drug cis-diamminedichloroplatinum(II).

Eitemau Tebyg

• Characterization of the ternary complexes formed in the reaction of cis-diamminedichloroplatinum (II), ethidium bromide and nucleic acids.
  gan: Malinge, J M, et al.
  Cyhoeddwyd: (1987)
• Alteration and activation of sequence-specific cleavage of DNA by bleomycin in the presence of the antitumor drug cis-diamminedichloroplatinum(II).
  gan: Mascharak, P K, et al.
  Cyhoeddwyd: (1983)
• Antibodies elicited against cis-diamminedichloroplatinum(II)-modified DNA are specific for cis-diamminedichloroplatinum(II)-DNA adducts formed in vivo and in vitro.
  gan: Poirier, M C, et al.
  Cyhoeddwyd: (1982)
• Mutagenic and genotoxic effects of DNA adducts formed by the anticancer drug cis-diamminedichloroplatinum(II).
  gan: Yarema, K J, et al.
  Cyhoeddwyd: (1995)
• The major adduct of the antitumor drug cis-diamminedichloroplatinum(II) with DNA bends the duplex by approximately equal to 40 degrees toward the major groove.
  gan: Rice, J A, et al.
  Cyhoeddwyd: (1988)