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Monoclonal antibodies to DNA modified with cis- or trans-diamminedichloroplatinum(II).

Murine monoclonal antibodies that bind selectively to adducts formed on DNA by the antitumor drug cis-diamminedichloroplatinum(II), cis-DDP, or to the chemotherapeutically inactive trans isomer trans-DDP were elicited by immunization with calf thymus DNA modified with either cis- or trans-DDP at rat...

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Hlavní autoři: Sundquist, W I, Lippard, S J, Stollar, B D
Médium: Artigo
Jazyk:Inglês
Vydáno: 1987
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC299514/
https://ncbi.nlm.nih.gov/pubmed/2446320
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