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Monoclonal antibodies to DNA modified with cis- or trans-diamminedichloroplatinum(II).
Murine monoclonal antibodies that bind selectively to adducts formed on DNA by the antitumor drug cis-diamminedichloroplatinum(II), cis-DDP, or to the chemotherapeutically inactive trans isomer trans-DDP were elicited by immunization with calf thymus DNA modified with either cis- or trans-DDP at rat...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
1987
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC299514/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2446320/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.84.23.8225 |
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