Formation of cis-diamminedichloroplatinum(II) 1,2-intrastrand cross-links on DNA is flanking-sequence independent

Mapping of cis-diamminedichloroplatinum(II) (cis-DDP, cisplatin) DNA adducts over >3000 nucleotides was carried out using a replication blockage assay. The sites of inhibition of modified T4 DNA polymerase, also referred to as stop sites, were analyzed to determine the effects of local sequence cont...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Burstyn, Judith N., Heiger-Bernays, Wendy J., Cohen, Seth M., Lippard, Stephen J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 2000
Assuntos:	Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC113142/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11058123/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.21.4237
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