Isolation of cDNAs encoding a human protein that binds selectively to DNA modified by the anticancer drug cis-diamminedichloroplatinum(II)

DNA modified by the antitumor drug cis-diamminedichloroplatinum(II) (cis-DDP or cisplatin) was used to identify a factor in mammalian cells that binds to cis-DDP-damaged DNA and hence may play a role in repair. This factor selectively recognizes double-stranded DNA fragments modified by cis-DDP or [...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Toney, J H, Donahue, B A, Kellett, P J, Bruhn, S L, Essigmann, J M, Lippard, S J
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1989
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298274/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2530581/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8328
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