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Isolation of cDNAs encoding a human protein that binds selectively to DNA modified by the anticancer drug cis-diamminedichloroplatinum(II)

DNA modified by the antitumor drug cis-diamminedichloroplatinum(II) (cis-DDP or cisplatin) was used to identify a factor in mammalian cells that binds to cis-DDP-damaged DNA and hence may play a role in repair. This factor selectively recognizes double-stranded DNA fragments modified by cis-DDP or [...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Toney, J H, Donahue, B A, Kellett, P J, Bruhn, S L, Essigmann, J M, Lippard, S J
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1989
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC298274/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2530581/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.21.8328
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