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Structural Basis for the cAMP-dependent Gating in the Human HCN4 Channel
Hyperpolarization-activated cAMP-regulated (HCN) channels play important physiological roles in both cardiovascular and central nervous systems. Among the four HCN isoforms, HCN2 and HCN4 show high expression levels in the human heart, with HCN4 being the major cardiac isoform. The previously publis...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978636/ https://ncbi.nlm.nih.gov/pubmed/20829353 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.152033 |
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