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Inner activation gate in S6 contributes to the state-dependent binding of cAMP in full-length HCN2 channel
Recently, applications of the patch-clamp fluorometry (PCF) technique in studies of cyclic nucleotide–gated (CNG) and hyperpolarization-activated, cyclic nucleotide–regulated (HCN) channels have provided direct evidence for the long-held notion that ligands preferably bind to and stabilize these cha...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Rockefeller University Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3382721/ https://ncbi.nlm.nih.gov/pubmed/22689828 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110749 |
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