Normal-Mode-Analysis-Guided Investigation of Crucial Intersubunit Contacts in the cAMP-Dependent Gating in HCN Channels

Protein structures define a complex network of atomic interactions in three dimensions. Direct visualization of the structure and analysis of the interaction potential energy are not straightforward approaches to pinpoint the atomic contacts that are crucial for protein function. We used the tetrame...

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Detalhes bibliográficos
Main Authors: Marni, Farzana, Wu, Shengjun, Shah, Gaurav M., Xu, Xin-ping, Hackett, Amber R., Xie, Changan, Shrestha, Sabisha, Liu, Lin, Liu, Qinglian, Zhou, Lei
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2012
Assuntos:
Channels and Transporters
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388215/
https://ncbi.nlm.nih.gov/pubmed/22828328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.05.030
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