Normal-Mode-Analysis-Guided Investigation of Crucial Intersubunit Contacts in the cAMP-Dependent Gating in HCN Channels

Protein structures define a complex network of atomic interactions in three dimensions. Direct visualization of the structure and analysis of the interaction potential energy are not straightforward approaches to pinpoint the atomic contacts that are crucial for protein function. We used the tetrame...

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Библиографические подробности
Главные авторы: Marni, Farzana, Wu, Shengjun, Shah, Gaurav M., Xu, Xin-ping, Hackett, Amber R., Xie, Changan, Shrestha, Sabisha, Liu, Lin, Liu, Qinglian, Zhou, Lei
Формат: Artigo
Язык:Inglês
Опубликовано: The Biophysical Society 2012
Предметы:
Channels and Transporters
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388215/
https://ncbi.nlm.nih.gov/pubmed/22828328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.05.030
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