Normal-Mode-Analysis-Guided Investigation of Crucial Intersubunit Contacts in the cAMP-Dependent Gating in HCN Channels

Protein structures define a complex network of atomic interactions in three dimensions. Direct visualization of the structure and analysis of the interaction potential energy are not straightforward approaches to pinpoint the atomic contacts that are crucial for protein function. We used the tetrame...

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Dades bibliogràfiques
Autors principals: Marni, Farzana, Wu, Shengjun, Shah, Gaurav M., Xu, Xin-ping, Hackett, Amber R., Xie, Changan, Shrestha, Sabisha, Liu, Lin, Liu, Qinglian, Zhou, Lei
Format: Artigo
Idioma:Inglês
Publicat: The Biophysical Society 2012
Matèries:
Channels and Transporters
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3388215/
https://ncbi.nlm.nih.gov/pubmed/22828328
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.05.030
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