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Inhibition of Bak Activation by VDAC2 Is Dependent on the Bak Transmembrane Anchor
Bax and Bak are pro-apoptotic factors that are required for cell death by the mitochondrial or intrinsic pathway. Bax is found in an inactive state in the cytosol and upon activation is targeted to the mitochondrial outer membrane where it releases cytochrome c and other factors that cause caspase a...
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| Главные авторы: | , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Biochemistry and Molecular Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978617/ https://ncbi.nlm.nih.gov/pubmed/20851889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.159301 |
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