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Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis
Mitochondrial outer membrane permeabilisation (MOMP) is the point of no return in many forms of apoptotic cell death. The killing effect of MOMP is twofold; it both initiates a proteolytic cascade of pro-apoptotic enzymes and damages mitochondrial function. Accordingly, prevention of MOMP can rescue...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Company of Biologists
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736138/ https://ncbi.nlm.nih.gov/pubmed/19795525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.038166 |
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