Wird geladen...

Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis

Mitochondrial outer membrane permeabilisation (MOMP) is the point of no return in many forms of apoptotic cell death. The killing effect of MOMP is twofold; it both initiates a proteolytic cascade of pro-apoptotic enzymes and damages mitochondrial function. Accordingly, prevention of MOMP can rescue...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Dewson, Grant, Kluck, Ruth M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Company of Biologists 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2736138/
https://ncbi.nlm.nih.gov/pubmed/19795525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.038166
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!