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Mechanisms by which Bak and Bax permeabilise mitochondria during apoptosis
Mitochondrial outer membrane permeabilisation (MOMP) is the point of no return in many forms of apoptotic cell death. The killing effect of MOMP is twofold; it both initiates a proteolytic cascade of pro-apoptotic enzymes and damages mitochondrial function. Accordingly, prevention of MOMP can rescue...
Αποθηκεύτηκε σε:
| Κύριοι συγγραφείς: | , |
|---|---|
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Company of Biologists
2009
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2736138/ https://ncbi.nlm.nih.gov/pubmed/19795525 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.038166 |
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