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Requirement of TGFβ Signaling for SMO-mediated Carcinogenesis
Hedgehog (Hh) signaling, via the key signal transducer Smoothened (SMO) and Gli transcription factors, is essential for embryonic development and carcinogenesis. At present, the molecular mechanism of Hh signaling-mediated carcinogenesis is not completely understood. Using a mouse model (K14cre/R26S...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978585/ https://ncbi.nlm.nih.gov/pubmed/20858897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.164442 |
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