Transforming Growth Factor β (TGF-β)-Smad Target Gene Protein Tyrosine Phosphatase Receptor Type Kappa Is Required for TGF-β Function

Transforming growth factor β (TGF-β) inhibits proliferation and promotes cell migration. In TGF-β-treated MCF10A mammary epithelial cells overexpressing HER2 and by chromatin immunoprecipitation, we identified novel Smad targets including protein tyrosine phosphatase receptor type kappa (PTPRK). TGF...

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Detalles Bibliográficos
Autores principales: Wang, Shizhen Emily, Wu, Frederick Y., Shin, Incheol, Qu, Shimian, Arteaga, Carlos L.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2005
Materias:
Signal Transduction
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1140650/
https://ncbi.nlm.nih.gov/pubmed/15899872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.25.11.4703-4715.2005
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