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A Role for Transcription Factor STAT3 Signaling in Oncogene Smoothened-driven Carcinogenesis

Activation of the Hedgehog (Hh) pathway is known to drive development of basal cell carcinoma and medulloblastomas and to associate with many other types of cancer, but the exact molecular mechanisms underlying the carcinogenesis process remain elusive. We discovered that skin tumors derived from ep...

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Detalhes bibliográficos
Main Authors: Gu, Dongsheng, Fan, Qipeng, Zhang, Xiaoli, Xie, Jingwu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3488104/
https://ncbi.nlm.nih.gov/pubmed/22992748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.377382
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