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Requirement of TGFβ Signaling for SMO-mediated Carcinogenesis
Hedgehog (Hh) signaling, via the key signal transducer Smoothened (SMO) and Gli transcription factors, is essential for embryonic development and carcinogenesis. At present, the molecular mechanism of Hh signaling-mediated carcinogenesis is not completely understood. Using a mouse model (K14cre/R26S...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
American Society for Biochemistry and Molecular Biology
2010
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2978585/ https://ncbi.nlm.nih.gov/pubmed/20858897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.C110.164442 |
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