Hypermethylation of PTGER2 Confers Prostaglandin E(2) Resistance in Fibrotic Fibroblasts from Humans and Mice

Idiopathic pulmonary fibrosis (IPF) is a devastating lung disease that is characterized by excessive proliferation of fibroblasts. The lipid mediator prostaglandin E(2) (PGE(2)) has the capacity to limit fibrosis through its inhibition of numerous functions of these fibroblasts; however, in the sett...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Huang, Steven K., Fisher, Aaron S., Scruggs, Anne M., White, Eric S., Hogaboam, Cory M., Richardson, Bruce C., Peters-Golden, Marc
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Investigative Pathology 2010
Schlagworte:
Regular Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966784/
https://ncbi.nlm.nih.gov/pubmed/20889571
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100446
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge