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Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts

Although the recruitment of fibroblasts to areas of injury is critical for wound healing, their subsequent apoptosis is necessary in order to prevent excessive scarring. Fibroproliferative diseases, such as pulmonary fibrosis, are often characterized by fibroblast resistance to apoptosis, but the me...

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Detalhes bibliográficos
Main Authors: Huang, S K, Scruggs, A M, Donaghy, J, Horowitz, J C, Zaslona, Z, Przybranowski, S, White, E S, Peters-Golden, M
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674355/
https://ncbi.nlm.nih.gov/pubmed/23640463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.146
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