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Histone modifications are responsible for decreased Fas expression and apoptosis resistance in fibrotic lung fibroblasts

Although the recruitment of fibroblasts to areas of injury is critical for wound healing, their subsequent apoptosis is necessary in order to prevent excessive scarring. Fibroproliferative diseases, such as pulmonary fibrosis, are often characterized by fibroblast resistance to apoptosis, but the me...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Huang, S K, Scruggs, A M, Donaghy, J, Horowitz, J C, Zaslona, Z, Przybranowski, S, White, E S, Peters-Golden, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3674355/
https://ncbi.nlm.nih.gov/pubmed/23640463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2013.146
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