Expression, purification and crystallization of adenosine 1408 aminoglycoside-resistance rRNA methyltransferases for structural studies

High-level resistance to a broad spectrum of aminoglycoside antibiotics can arise through either N7-methyl guanosine 1405 (m(7)G1405) or N1-methyl adenosine 1408 (m(1)A1408) modifications at the drug binding site in the bacterial 30S ribosomal subunit decoding center. Two distinct families of 16S ri...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Zelinskaya, Natalia, Rankin, C. Robert, Macmaster, Rachel, Savic, Miloje, Conn, Graeme L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2966526/
https://ncbi.nlm.nih.gov/pubmed/20667473
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.pep.2010.07.005
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!

Ähnliche Einträge