Assessing energetic contributions to binding from a disordered region in a protein-protein interaction

Many functional proteins are at least partially disordered prior to binding. Although the structural transitions upon binding of disordered protein regions can influence the affinity and specificity of protein complexes, their precise energetic contributions to binding are unknown. Here, we use a mo...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Cho, Sangwoo, Swaminathan, Chittoor P., Bonsor, Daniel A., Kerzic, Melissa C., Guan, Rongjin, Yang, Jianying, Kieke, Michele C., Andersen, Peter S., Kranz, David M., Mariuzza, Roy A., Sundberg, Eric J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2010
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964404/
https://ncbi.nlm.nih.gov/pubmed/20836565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1008968
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