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Assessing energetic contributions to binding from a disordered region in a protein-protein interaction

Many functional proteins are at least partially disordered prior to binding. Although the structural transitions upon binding of disordered protein regions can influence the affinity and specificity of protein complexes, their precise energetic contributions to binding are unknown. Here, we use a mo...

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Detalhes bibliográficos
Main Authors: Cho, Sangwoo, Swaminathan, Chittoor P., Bonsor, Daniel A., Kerzic, Melissa C., Guan, Rongjin, Yang, Jianying, Kieke, Michele C., Andersen, Peter S., Kranz, David M., Mariuzza, Roy A., Sundberg, Eric J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2964404/
https://ncbi.nlm.nih.gov/pubmed/20836565
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi1008968
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