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Molecular Architecture of the Major Histocompatibility Complex Class I-binding Site of Ly49 Natural Killer Cell Receptors

Natural killer (NK) cells play a vital role in the detection and destruction of virally infected and tumor cells during innate immune responses. The highly polymorphic Ly49 family of NK receptors regulates NK cell function by sensing major histocompatibility complex class I (MHC-I) molecules on targ...

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Main Authors: Deng, Lu, Cho, Sangwoo, Malchiodi, Emilio L., Kerzic, Melissa C., Dam, Julie, Mariuzza, Roy A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423261/
https://ncbi.nlm.nih.gov/pubmed/18426793
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801526200
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